Overview
CML is characterized by Philadelphia chromosome, BCR-ABL fusion.
Symptoms
- •Fatigue
- •Splenomegaly
- •Weight loss
- •Night sweats
Diagnosis
- ✓Blood count
- ✓BCR-ABL PCR
- ✓Bone marrow
- ✓FISH
Treatments
- →Imatinib
- →Dasatinib
- →Nilotinib
- →Stem cell transplant (rare)
Risk Factors
⚠️Radiation exposure
Key Facts
- ℹ️>90% achieve MMR with TKI
- ℹ️Chronic phase: excellent prognosis
ICD-10: C92.1 | Prevalence: yaygın
Last updated: 11/9/2025