Overview
DLBCL is the most common aggressive non-Hodgkin lymphoma.
Symptoms
- •Lymphadenopathy
- •B symptoms (fever, night sweats, weight loss)
- •Pain
Diagnosis
- ✓Biopsy
- ✓IHC (CD20+)
- ✓PET-CT
- ✓Bone marrow
Treatments
- →R-CHOP
- →Radiation
- →Stem cell transplant (relapse)
Risk Factors
⚠️Age >60
⚠️EBV
⚠️Autoimmune diseases
Key Facts
- ℹ️60-70% cure rate with R-CHOP
- ℹ️IPI prognostic score
ICD-10: C83.3 | Prevalence: yaygın
Last updated: 11/9/2025