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Germ Cell Tumors

Ovarian Cancer

Overview

Germ cell tumors arise from primitive germ cells and are most common in adolescents and young women.

Symptoms

  • Abdominal pain
  • Pelvic mass
  • Irregular periods
  • hCG/AFP elevation

Diagnosis

  • Tumor markers (AFP, β-hCG, LDH)
  • Ultrasound
  • CT
  • Biopsy

Treatments

  • Unilateral salpingo-oophorectomy
  • BEP (Bleomycin, Etoposide, Cisplatin)

Risk Factors

⚠️Gonadal dysgenesis
⚠️Cryptorchidism (in males)
⚠️Family history

Key Facts

  • ℹ️>90% cure rate with chemotherapy
  • ℹ️Peak age 10-30

ICD-10: C56 | Prevalence: nadir

Last updated: 11/9/2025

Germ Hücreli Tümörler: Belirtiler ve Tedavi