Overview
High-grade serous carcinoma is the most aggressive and common subtype of epithelial ovarian cancer.
Symptoms
- •Ascites
- •Abdominal distension
- •Weight loss
- •Fatigue
Diagnosis
- ✓CA-125 elevation
- ✓CT/PET-CT
- ✓Biopsy
- ✓p53 mutation
Treatments
- →Debulking surgery
- →Carboplatin + Paclitaxel
- →Bevacizumab
- →Olaparib
Risk Factors
⚠️BRCA1/2
⚠️HNPCC
⚠️Age >50
⚠️Nulliparity
Key Facts
- ℹ️~70% of epithelial ovarian cancers
- ℹ️Often diagnosed at stage III-IV
ICD-10: C56 | Prevalence: yaygın
Last updated: 11/9/2025