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Non-Small Cell Lung Cancer (NSCLC)

Lung Cancer

Overview

NSCLC is the most common type of lung cancer, making up 85% of cases. It grows slower than small cell lung cancer.

Symptoms

  • Persistent cough
  • Shortness of breath
  • Chest pain
  • Coughing up blood
  • Unexplained weight loss
  • Fatigue

Stages

Stage IAStage IBStage IIAStage IIBStage IIIAStage IIIBStage IV

Diagnosis

  • Low-dose CT scan
  • Chest X-ray
  • PET-CT
  • Bronchoscopy
  • Biopsy
  • Molecular testing (EGFR, ALK, ROS1, PD-L1)

Treatments

  • Surgery (lobectomy, segmentectomy)
  • Radiation therapy
  • Chemotherapy
  • Immunotherapy (pembrolizumab, nivolumab)
  • Targeted therapy (osimertinib, alectinib)

Risk Factors

⚠️Smoking
⚠️Secondhand smoke
⚠️Radon exposure
⚠️Asbestos
⚠️Family history

Key Facts

  • ℹ️5-year survival: 63% (Stage I), 6% (Stage IV)
  • ℹ️EGFR mutation common in non-smokers
  • ℹ️Annual low-dose CT recommended for ages 50-80 with smoking history

ICD-10: C34.9 | Prevalence: çok yaygın

Last updated: 11/9/2025

Küçük Hücre Dışı Akciğer Kanseri (NSCLC): Belirtiler, Evreler ve Tedavi