Overview
PNETs are rare, may be functional (hormone-secreting) or non-functional.
Symptoms
- •Hypoglycemia (insulinoma)
- •Ulcers (gastrinoma)
- •Abdominal pain
- •Weight loss
Diagnosis
- ✓Chromogranin A
- ✓CT/MRI
- ✓EUS
- ✓Ga-68 DOTATATE PET
Treatments
- →Surgical resection
- →Somatostatin analogs
- →Everolimus
- →PRRT
Risk Factors
⚠️MEN1
⚠️VHL
⚠️NF1
Key Facts
- ℹ️<5% of pancreatic tumors
- ℹ️Better prognosis than PDAC
ICD-10: C25.4 | Prevalence: nadir
Last updated: 11/9/2025