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Peptic Ulcer Disease

Gastroduodenal Disease

Overview

Peptic ulcer is a mucosal defect in stomach or duodenum, mainly due to H.pylori or NSAIDs.

Symptoms

  • Epigastric pain
  • Nausea
  • Hematemesis
  • Melena

Diagnosis

  • Endoscopy
  • H.pylori test (urea breath, stool, biopsy)
  • CBC

Treatments

  • PPI
  • Amoxicillin + Clarithromycin (H.pylori)
  • Avoid NSAIDs

Risk Factors

⚠️H.pylori
⚠️NSAIDs
⚠️Smoking
⚠️Stress

Key Facts

  • ℹ️H.pylori 70-90% duodenal
  • ℹ️Zollinger-Ellison rare

ICD-10: K25-K27 | Prevalence: yaygın

Last updated: 11/9/2025

Peptik Ülser Hastalığı: Belirtiler ve Tedavi